Colistin 5% Powder M70

• 💊 Colistin 5% Powder – General Description

Generic name: Colistin (also known as Polymyxin E)
Pharmaceutical form: Powder (for oral use in animals or for reconstitution, depending on formulation)
Concentration: 5% (i.e., 50 mg of colistin per gram of product, depending on manufacturer)

⚙️ Composition

• Active ingredient: Colistin (as colistin sulfate or colistimethate sodium) – 5%

• Excipients: Inert carrier (such as lactose or dextrose) up to 100%

🧫 Mechanism of Action

Colistin is a polypeptide antibiotic that acts by disrupting the bacterial cell membrane, causing leakage of cellular contents and bacterial death.
It is mainly effective against Gram-negative bacteria, including:

• Escherichia coli

• Salmonella spp.

• Klebsiella spp.

• Pseudomonas aeruginosa

🐄 Common Uses (Veterinary)

Colistin 5% powder is widely used in veterinary medicine (poultry, swine, calves) for the treatment and prevention of gastrointestinal infections caused by susceptible Gram-negative bacteria, such as:

• Bacterial enteritis

• Colibacillosis

• Salmonellosis

💧 Route of Administration

• Oral use, usually administered through drinking water or feed
  (Dosage depends on animal species, weight, and severity of infection)

⚠️ Precautions

• Do not use in animals with hypersensitivity to colistin.

• Observe withdrawal periods before slaughter or milk/egg collection.

• Overuse can lead to antimicrobial resistance, so use under veterinary supervision.